EXPERIMENTAL EPIDEMIOLOGY

Experimental Epidemiology

In this paper we have described the first part of an experimental study of the epidemiology of mouse typhoid. One set of data has been presented on the basis of which little or no analysis has been attempted. The immediate object has been rather to collect materials than to undertake to account for the phenomena encountered. It is obvious that the factors involved in the inquiry are intricate, ...

Experimental Epidemiology of Tuberculosis

1. Normal guinea pigs exposed to tuberculous cage mates infected intraperitoneally and with no cutaneous ulceration readily contract spontaneous tuberculosis. 2. The incidence of spontaneous tuberculosis increases with the intensity and with the duration of exposure. 3. Spontaneous tuberculosis acquired from infected cage mates has with few exceptions the characters of an infection which has en...

Experimental Epidemiology of Tuberculosis

1. Hereditary resistance to attack by air-borne tubercle bacilli is distinct from the resistance to the ensuing disease. 2. One inbred rabbit family has little resistance to attack: by the microorganism but has considerable resistance against the ensuing disease. 3. Another inbred family has considerable resistance against attack by the tubercle bacillus but has little resistance against the en...

Epidemiology for the uninitiated. Experimental studies.

Stochastic environmental fluctuations drive epidemiology in experimental host-parasite metapopulations.

Environmental fluctuations are important for parasite spread and persistence. However, the effects of the spatial and temporal structure of environmental fluctuations on host-parasite dynamics are not well understood. Temporal fluctuations can be random but positively autocorrelated, such that the environment is similar to the recent past (red noise), or random and uncorrelated with the past (w...